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Updated: Jun 25, 2025

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固态振动循环二元化用于制药应用:索福斯布维尔的多态和共晶

Adam Sklenář1, Lucie Růžičková2, Věra Schrenková3

  • 1Institute of Organic Chemistry and Biochemistry of the CAS, Flemingovo nám.2, Prague 166 10, Czech Republic; University of Chemistry and Technology, Prague, Technická 5, Prague 166 28, Czech Republic.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
|May 24, 2024
PubMed
概括

振动循环二元化 (VCD) 光谱为识别晶体结构提供了对X射线衍射的经济有效和高效的替代方案. 这项研究优化了用于制药应用的VCD方法,证明了其区分多态和共晶的能力.

关键词:
氨基酸是氨基酸的组成部分.氧酸是一种氧酸.多态的多态体.索福斯布维尔 (Sofosbuvir) 是一种药物.固态硬件是一种固态硬件.振动的圆形二元化是什么?

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