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功能衰竭患者队列中的手握强度和死亡率:不同规范化方法的比较分析
Mohamed E Suliman1, Kakei Ryu2, Abdul Rashid Qureshi1
1Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Nutrition (Burbank, Los Angeles County, Calif.)
|May 24, 2024
概括
减少手握强度 (HGS) 与糟糕的结果有关. 在透析患者中,参考组的HGS百分比 (HGS%) 比绝对或正常化的HGS更好地预测死亡率,改善生存歧视.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床医学 临床医学
- 老年病的医生 老年病的医生
背景情况:
- 减少握力 (HGS) 是已知的不良临床结果的指标.
- 在透析患者中评估HGS对于预测死亡风险至关重要.
研究的目的:
- 为了比较不同HGS正常化方法在预测透析患者死亡风险方面的有效性.
- 要确定HGS,当表达为参考组 (HGS%) 的百分比时,与绝对或体型规范化的HGS相比,是死亡率的优异预测指标.
主要方法:
- 分析了446名发生透析患者的队列.
- 使用各种方法测量和正常化HGS:绝对,正常化到身高,体重,BMI,并作为性别匹配对照的百分比 (HGS%).
- 接收器运行特征曲线 (AUROC) 下的面积比较了预测准确性;竞争风险回归评估了死亡风险.
主要成果:
- 与绝对值或正常化HGS值相比,HGS%显示出更高的AUROC.
- 较低HGS%的第三种动物独立地与明显更高的全因死亡风险相关.
- 患者在最高的HGS%三位数存活时间比中等和低三位数的患者长.
结论:
- HGS%是发生透析患者全因死亡率的强有力的预测指标.
- HGS%提供了优越的生存歧视与绝对HGS或按身体尺寸规范的HGS相比.
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