巴西的短期PM2.5暴露和时间变化的癌症死亡风险
Pei Yu1, Rongbin Xu1, Yao Wu1
1Climate Air quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Journal of hazardous materials
|May 24, 2024
概括
短期暴露于细颗粒物 (PM2.5) 与巴西多个地区癌症死亡率的增加有关. 虽然风险已经下降,但对于癌症患者来说,避免PM2.5仍然至关重要.
科学领域:
- 环境流行病学环境流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 对短期PM2.5暴露对各种癌症死亡率地点的影响的理解有限.
- 以前的研究主要集中在肺癌死亡人数上.
研究的目的:
- 从巴西的25个常见癌症部位量化短期PM2.5暴露和死亡率之间的联系.
- 评估空气污染对全国癌症死亡率的影响.
主要方法:
- 时间分层的案例交叉研究设计.
- 利用来自巴西死亡信息系统 (2000-2019年) 的个人癌症死亡数据.
- 分析了在市级汇总的每日PM2.5度.
主要成果:
- 3天平均PM2.5暴露量增加10μg/m3与所有癌症死亡率增加4%有关 (OR 1.04).
- 在食道,胃,结肠直肠,肺,乳腺,前列腺和白血病的癌症中发现了重要的关联.
- 在研究期间,估计有1,917,994例因急性PM2.5暴露而导致的癌症死亡.
结论:
- 急性PM2.5暴露与增加的整体和特定癌症死亡率有显著的关联.
- 尽管下降趋势,但PM2.5暴露继续对癌症患者构成风险.
- 这些发现强调了在癌症护理和公共卫生倡议中,需要制定战略,尽量减少PM2.5暴露.
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