高流量鼻氧用于儿童呼吸道手术,以减少缺氧事件:一个随机对照试验
Susan Humphreys1, Britta S von Ungern-Sternberg2, Fiona Taverner3
1Department of Anaesthesia, Queensland Children's Hospital, Brisbane, QLD, Australia; The University of Queensland, Brisbane, QLD, Australia.
The Lancet. Respiratory medicine
|May 24, 2024
概括
与标准护理相比,鼻腔高流氧并没有减少无管儿科气道手术期间的中断. 这两种氧气方法都适合在这些复杂的程序中维持氧化.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 呼吸系统护理 呼吸系统护理
- 手术手术手术手术手术手术手术手术手术手术
背景情况:
- 儿童的无管上呼吸道手术是复杂的,需要共享的操作领域,并且经常被救援氧气治疗中断.
- 鼻腔高流氧在减少这些中断的有效性尚未得到充分证实.
研究的目的:
- 评估鼻腔高流氧在减少无管儿科上呼吸道手术期间的救援氧化中断方面的有效性.
- 为了比较鼻腔高流氧和标准氧气治疗之间的低血事件和不良事件的发生率.
主要方法:
- 一个多中心随机试验,涉及483名儿童 (0-16岁) 接受无管上呼吸道手术.
- 参与者被随机分配,接受鼻腔高流氧或标准氧气治疗.
- 主要结局是成功麻醉,不间断进行救援氧化;次要结局包括缺血事件和不良事件.
主要成果:
- 在高流氧组和标准护理组 (调整后风险比1.02,p=0.82) 88%的手术中,成功无中断麻醉.
- 低血事件发生在高流组的19%和标准护理组的22% (RR 0.86).
- 两组之间没有观察到二次结果或不良事件的显著差异.
结论:
- 在无管儿科上呼吸道手术期间,与标准氧相比,高流量鼻氧不会减少用于救援氧化的程序中断.
- 鼻腔高通量和标准氧都是维持这种患者群体中氧化的合适替代方案.
- 该研究发现,这两种氧气输送方法之间的不良事件没有显著差异.
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