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作为大核细胞激活的调节者,LAT风静态

Alyssa J Moroi1, Peter J Newman1,2,3

  • 1Blood Research Institute, Versiti Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.

Thrombosis and haemostasis
|May 24, 2024
PubMed
概括

将T细胞激活链接蛋白 (LAT) 中的特定甘氨酸改为酸性残留物可以增强巨核细胞中ITAM受体的信号传递. 这种修饰增强了LAT酸化和血小板形成,在血小板生物工程中具有潜在的应用.

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