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Updated: Jun 25, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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在非酒精性脂肪肝炎患者中发现ZSP1601的剂量,使用人口药理动力学和暴露-反应方法

Haijun Li1, Yue Hu2, Yuting Yang3

  • 1Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, China; Guangdong Raynovent Biotech Co., Ltd, Guangzhou, China.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|May 24, 2024
PubMed
概括

这项研究开发了ZSP1601,一种新的NAFLD治疗方法的种群药动力学模型. 该模型通过将ZSP1601暴露与疗效和安全结果联系起来来指导最佳剂量.

关键词:
暴露反应时间在健康的志愿者身上.患有非酒精性脂肪肝炎的患者人口的药理动力学.ZSP160101 这是一个很好的选择.

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