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排泄基因单核酸变体与耐药性相关,在Mycobacterium结核病菌与不一致的药物基因型的隔离物中

Zahra Hasan1, Safina Abdul Razzak1, Akbar Kanji1

  • 1Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.

Journal of global antimicrobial resistance
|May 24, 2024
PubMed
概括

结核菌流出中的单核酸变体 (SNV) 与多药性耐药性 (MDR) 有关,包括广泛耐药性 (XDR) 菌株. 分析这些SNV可以更好地了解耐药性,特别是在具有冲突的遗传和表型数据的情况下.

关键词:
药物耐药性 药物耐药性 药物耐药性排气 (EP) 是一种排气.基因组学就是基因组学.结核病菌菌菌的结核病菌的结核病菌.

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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