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Updated: Jun 25, 2025

A Simple Pit Assay Protocol to Visualize and Quantify Osteoclastic Resorption In Vitro
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在炎症微环境下,PGC-1α/LDHA信号促进了糖解的启动,以调节机械诱导的骨重塑

Jiani Liu1, Jixiao Wang1, Ziyao Wang1

  • 1Department of Orthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Center for Oral Diseases, Jinan 250012, Shandong, China.

Bone
|May 24, 2024
PubMed
概括

炎症通过改变细胞代谢来破坏机械力下的骨重塑. 通过PGC-1α和LDHA调节的增强糖解,可以抵消氧化酸化对骨修复的负面影响.

关键词:
骨改造 骨改造 骨改造 骨改造葡萄糖的新陈代谢.炎症 炎症是一种炎症.拉达 (LDHA) 是一个机械力是一种力.它们是PGC-1α.

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