在新生儿高频振荡呼吸器中振荡体积和振荡压力之间的关系:一个体外研究
Emanuela Zannin1, Camilla Rigotti2, Raffaele L Dellacà3
1Neonatal Intensive Care Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Archives of disease in childhood
|May 24, 2024
概括
新生儿高频振荡式 (HFO) 呼吸机存在很高的变化,影响了传递的振荡体积 (VOSC) 和压力振幅 (ΔP) 的准确性. 这些差异影响了患者的护理,需要仔细选择呼吸机.
科学领域:
- 新生儿医学 新生儿医学
- 呼吸系统护理 呼吸系统护理
- 生物医学工程 生物医学工程
背景情况:
- 高频振荡式 (HFO) 通风对于新生儿呼吸支至关重要.
- 精确传递振荡体积 (VOSC) 和压力振幅 (ΔP) 对于有效的HFO治疗至关重要.
- 呼吸机性能的变化可能会影响临床结果.
研究的目的:
- 在6台新生儿HFO呼吸器中分析VOSC和ΔP之间的关系.
- 为了评估这些设备中VOSC和ΔP测量的准确性.
- 为了评估每个通风器提供的最大 ΔP.
主要方法:
- 一项体外研究使用6台新生儿HFO呼吸器进行.
- 通过调整呼吸机设置和测试肺部特征,创建模拟的早产和终产新生儿肺部状况.
- 对VOSC和ΔP进行测量,并与使用线性回归和布兰德-阿尔特曼分析的参考系统进行比较.
主要成果:
- 在不同的呼吸机中,观察到针对目标VOSC的显示 ΔP 中存在显著的变化.
- 大多数通风机显示过度读取 ΔP (高达 30 cmH2O或 60%) 和 VOSC (高达 ±2 mL或 ±30%).
- SLE6000显示了最小的ΔP测量误差,而Fabian HFOi显示了最小的VOSC误差. 最大传递的ΔP不同,声视觉,SLE6000和SensorMedics 3100A显示最高.
结论:
- 在HFO通风器中VOSC-ΔP关系中观察到的变化主要是由于它们的ΔP和VOSC测量准确度的差异.
- 在HFO通风机模型之间存在最大产生的ΔP的显著差异.
- 这些发现强调了了解个体呼吸器性能特征对于优化新生儿呼吸支的重要性.
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