狭窄的LAD冠状动脉的欧勒里安-拉格兰吉安密集离散相模型 (DDPM) 与单相建模相比
Ziba Valizadeh1, Mehrzad Shams1, Hossein Dehghani1
1Faculty of Mechanical Engineering, K. N. Toosi University of Technology, Tehran, Iran.
Medical engineering & physics
|May 24, 2024
概括
这项研究使用了两相模型来模拟狭窄动脉中红细胞的运动. 密集离散相模型 (DDPM) 显示了较高的剪切应力和循环再循环区域,表明动脉样硬化风险增加.
科学领域:
- 计算流体动力学 计算流体动力学
- 生物医学工程 生物医学工程
- 血液动力学 血液动力学
背景情况:
- 红细胞的行为在计算流体动力学 (CFD) 中对于血液流量研究至关重要,特别是在狭窄动脉中.
- 了解红细胞运动对于分析复杂动脉几何结构中的血液动力学至关重要.
研究的目的:
- 为了研究红细胞运动对血流动力学的影响,在3D冠状动脉模型中使用变化的狭窄.
- 评估密集离散相模型 (DDPM) 在模拟粒子运动和血液动力学变化的有效性.
主要方法:
- 采用了使用密集离散阶段模型 (DDPM) 的多相CFD方案.
- 模拟是在3D冠状动脉几何学与不同程度的狭窄进行的.
- 血压用于输入/输出条件,假设动脉壁刚硬.
主要成果:
- DDPM模型的预测与实验数据有很好的一致性.
- 与单相模型相比,双相流动模拟显示出更高的剪切应力.
- 在DDPM建模中的循环再循环区域表明,在静脉缩前的区域,动脉样硬化斑块重新形成的可能性更高.
结论:
- DDPM对于计算动脉剪切应力和模拟粒子运动和再循环区域是有效的.
- 与单相模型相比,双相流量建模为血液动力学和狭窄动脉中的颗粒沉积提供了更准确的见解.
更多相关视频
06:18Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
Published on: December 6, 2024
494
09:20Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
6.4K
相关概念视频
Eulerian and Lagrangian Flow Descriptions
1.4K
Fluid flow analysis is critical in many scientific and engineering disciplines, and two principal approaches are used to describe this flow: the Eulerian and Lagrangian methods. These methods offer different perspectives on monitoring and analyzing the motion of fluids, each with distinct advantages depending on the scenario.
The Eulerian method focuses on fixed points in space where fluid properties, such as velocity, pressure, and temperature, are observed as the fluid moves between these...
The Eulerian method focuses on fixed points in space where fluid properties, such as velocity, pressure, and temperature, are observed as the fluid moves between these...
1.4K
Node Analysis for AC Circuits
316
Consider an angioplasty system featuring a catheter equipped with a turbine, a critical tool for removing plaque deposits from coronary arteries. This intricate medical device operates using a circuit model reminiscent of a dual-node RLC circuit powered by a current-controlled voltage source.
To unravel the complexities of this system, nodal analysis is employed, a powerful technique founded on Kirchhoff's current law (KCL), which remains valid for phasors. AC circuits can effectively be...
To unravel the complexities of this system, nodal analysis is employed, a powerful technique founded on Kirchhoff's current law (KCL), which remains valid for phasors. AC circuits can effectively be...
316
Typical Model Studies
354
Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
354
Steady, Laminar Flow Between Parallel Plates
173
Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
173
