在芝麻油鼻喷雾中使用花来改善鼻腔前庭炎症状:一项随机对照试验
Elizabeth J Cathcart-Rake1, Kimberly Steinert2, Deanne Smith3
1Department of Medical Oncology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. Cathcart-Rake.Elizabeth@mayo.edu.
概括
在芝麻油鼻喷雾中的花,有效地缓解了化疗患者的鼻腔前庭炎症状. 这种治疗为管理化疗相关的鼻不适提供了一个有希望的选择.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 鼻腔前庭炎是化疗的常见副作用之一.
- 癌症患者的鼻腔症状的有效管理对于治疗坚持和生活质量至关重要.
- NCT04620369 美国国家航空公司
研究的目的:
- 为了评估花在芝麻油 (RG) 鼻喷雾中的效果与同位素盐水 (IS) 鼻喷雾.
- 评估在接受化疗的患有鼻腔前庭炎的患者的症状缓解.
主要方法:
- 第三阶段随机双盲受控试验.
- 106名患者被随机分为1:1接受RG或IS鼻喷剂,每天两次,持续2周.
- 用于在基线和每周评估的鼻子症状问卷.
主要成果:
- 在RG手臂的67.4%的患者报告症状改善,而IS手臂的36.6% (P=0.009).
- 群体之间的人口统计和基线症状相似.
- 不良事件很少发生,在RG和IS手臂之间是可比的.
结论:
- 芝麻油鼻雾中的花显著改善了鼻腔前庭炎的症状.
- RG鼻喷雾是一种安全有效的选择,用于管理化疗引起的鼻症状.
相关概念视频
Drugs Used in Upper Respiratory Disorders: Overview
1.0K
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
1.0K
Nose and Nasal Cavity
16.7K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
16.7K
Epistaxis
791
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
791


