食物传播细菌病原体:基因组为复杂和不断变化的世界中的持久和新兴威胁的基因组为基础的方法
Alison E Mather1,2, Matthew W Gilmour3,4, Stuart W J Reid5
1Quadram Institute Bioscience, Norwich, UK. Alison.Mather@quadram.ac.uk.
Nature reviews. Microbiology
|May 24, 2024
概括
基因组工具通过跟踪细菌食品传播危害和了解病原体传播来提高食品安全. 将这些与食品系统洞察力相结合,可以改善整个供应链的风险评估和干预措施.
科学领域:
- 食品安全 食品安全
- 微生物生态学 微生物生态学
- 基因组学就是基因组学.
背景情况:
- 食物传播疾病带来了重大的健康和经济挑战,复杂的是不断发展的食品系统中的各种微生物危害.
- 自然,政治和商业驱动因素,以及气候变化和消费者偏好,不断改变粮食生产和病原体传播风险.
- 现有的食品安全干预措施很难跟上这些动态变化.
研究的目的:
- 审查基因组为基础的方法如何提高对食物传播细菌危害的理解.
- 突出基因组学在识别既定和新兴的食品传播威胁中的作用.
- 强调考虑微生物群落和食品系统动态对于有效的病原体控制的重要性.
主要方法:
- 基于基因组的方法的审查,包括全基因组和元基因组测序.
- 对微生物监测计划和食品系统洞察力的分析.
- 检查病原体的进化,传播和生态的研究.
主要成果:
- 基于基因组的方法为风险评估和食品安全干预提供了变革性的信息.
- 基因组学阐明了持久性细菌食品传播危害的进化和传播途径.
- 了解复杂的微生物群落对于病原体在食品系统中的持久性和传播至关重要.
结论:
- 基于基因组的策略对于现代食品安全至关重要,能够更好地跟踪和控制食源性病原体.
- 将基因组数据与食品系统知识相结合,可以积极地进行风险管理,以应对不断变化的威胁.
- 考虑微生物生态和食品系统变化的整体方法对于确保食品安全至关重要.
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