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在囊尿道狭窄中同时出现高频率的状形质形成症及其与重建延迟和尿道休息相关
Yusuke Hirano1, Akio Horiguchi2, Masayuki Shinchi1
1Department of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa-City, Saitama, 359-8513, Japan.
World journal of urology
|May 24, 2024
概括
状形质形成症 (SM) 在状尿道狭窄中很常见,影响了超过一半的患者. 较长的疾病持续时间和休息期间的空白预测了它的存在,影响了重建性手术的计划.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 病理学 病理学 病理学
- 手术重建手术重建的方法
背景情况:
- 凸轮尿道狭窄是一个重大的临床挑战.
- 状元形成 (SM) 是尿道狭窄形成的潜在前体.
- 了解SM的患病率和预测因素对于有效管理至关重要.
研究的目的:
- 为了确定囊尿道收缩中同时发生的状元形成症 (SM) 的患病率.
- 调查与SM存在相关的临床因素.
- 评估SM对切除和初级解剖 (EPA) 成功的影响.
主要方法:
- 对165名接受EPA治疗的男性患者进行了回顾性审查,以治疗腹膜尿道狭窄 (2010-2020年).
- 经验丰富的病理学家对经验丰富的病理学家对同时发生的MS的切除尿道样本进行组织学评估.
- 分析临床数据,包括疾病持续时间,病因和尿道休息期间的管理.
主要成果:
- 同时的MS在52.1%的患者中被发现.
- 患有MS的患者的中位疾病持续时间明显长 (38个月) 与没有MS的患者 (9个月).
- 独立的SM预测因素包括更长的疾病持续时间,非创伤性病因和尿道休息期间的空气.
结论:
- 同时的状形质变形是状尿道狭窄的频繁发现.
- 对于重建性泌尿科医生来说,对MS的认识很重要,特别是在长期疾病的病例中.
- 肌痛性脊髓瘤的存在并没有显著影响切除和初级解剖的成功率.
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