身体组成和内动脉瘤破裂的风险
Katja Løvik1, Johnny Laupsa-Borge2, Nicola Logallo3
1Department of Clinical Medicine, University of Bergen, Bergen, Norway. katja.lovik@gmail.com.
European journal of medical research
|May 24, 2024
概括
较低的身体脂肪百分比和体重与内动脉瘤破裂的风险更高有关,这挑战了肥胖悖论. 这项研究研究了超出BMI的人类测量变量在患有动脉瘤下arachnoid出血 (aSAH) 的患者.
科学领域:
- 神经外科 神经外科
- 血管神经学 血管神经学
- 肥胖医学 肥胖医学
背景情况:
- 由破裂的内动脉瘤引起的甲状腺下部出血 (SAH) 是危及生命的.
- 肥胖是一个日益严重的健康问题,伴有多种并发症.
- 矛盾的是,更高的体重指数 (BMI) 与SAH风险降低有关.
研究的目的:
- 调查人体指数之外的人类测量变量与内动脉瘤破裂风险之间的关联.
- 为了探索世界.
- 肥胖的悖论 肥胖的悖论
- 与动脉瘤下arachnoid出血 (aSAH) 相关.
主要方法:
- 对31名aSAH患者和28名未破裂动脉瘤 (UIA) 患者的身体组成进行生物电阻分析.
- 收集并发症和风险因素数据.
- 后勤回归用于分析人体测量变量与动脉瘤破裂之间的关联.
主要成果:
- 在体脂肪百分比和动脉瘤破裂之间发现了显著的反向关系 (OR:0.92 [0.86,0.97]).
- 身体脂肪质量也与动脉瘤破裂有显著的反向关系 (OR:0.95 [0.90,0.99]).
- 这些关联在年龄和性别调整后仍然显著.
结论:
- 下肢脂肪百分比和体重与内动脉瘤破裂的风险增加有关.
- 研究结果表明,BMI以外的因素有助于aSAH的"肥胖悖论".
- 需要使用更大的样本大小进行进一步的研究来证实这些关系.
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