探索共生多样性和分布在单细胞状原生体中的景观
Bing Zhang1,2,3, Liwen Xiao2, Liping Lyu4
1University of Chinese Academy of Sciences, Beijing, 100049, China.
Microbiome
|May 24, 2024
概括
这项研究揭示了与状动物一起生活的多样化的细菌群落,揭示了新的物种和共生模式. 它强调了宿主消化和细菌蛋白如何影响这些关键的真核生物-细菌关系.
科学领域:
- 微生物学 微生物学
- 亲生组织学 亲生组织学 亲生组织学
- 交生研究 交生研究
背景情况:
- 细胞-细菌共生是至关重要的,但在像状动物这样的单细胞原生体中了解得很少.
- 目前的知识主要集中在多细胞真核生物上,忽视了多样化的微生物真核生物.
研究的目的:
- 为了研究与单细胞状动物相关的细菌共生体.
- 描述与状动物共存的细菌和古生物的基因组多样性.
- 探索驱动状体-细菌共生关系的机制.
主要方法:
- 收集了246个状动物样本,这些样本来自Ciliophora类.
- 进行了基于单细胞的元基因组测序.
- 分析了细菌和古生物的基因组和共生模式.
主要成果:
- 确定了883种与状动物共存的细菌物种和7种与状动物共存的古生物学物种,其中包括116种新的细菌基因组.
- 超过90%的状动物宿主是细菌,每个宿主有多种细菌共生体,观察到七种不同的共生模式.
- 主体消化影响细胞内共生生物的多样性;细菌中的真核生物样蛋白质可能会增强宿主范围.
结论:
- 这是第一次大规模分析 prokaryotic 与状原生体的关联.
- 这项研究为真核-细菌共生研究提供了基础资源.
- 这些发现有助于我们更好地理解微生物相互作用和原生动物进化.
更多相关视频
09:35Fluorescently Labeled Bacteria as a Tracer to Reveal Novel Pathways of Organic Carbon Flow in Aquatic Ecosystems
Published on: September 13, 2019
7.1K
14:38Establishment of Microbial Eukaryotic Enrichment Cultures from a Chemically Stratified Antarctic Lake and Assessment of Carbon Fixation Potential
Published on: April 20, 2012
11.4K
相关概念视频
Prokaryotic Cells
122.1K
Prokaryotes are small unicellular organisms that include the domains—Archaea and Bacteria. Bacteria include many common organisms, such as Salmonella and E. coli, while the Archaea include extremophiles that live in harsh environments, such as volcanic springs.
Like eukaryotic cells, all prokaryotic cells are surrounded by a plasma membrane, have genetic material in the form of single, circular DNA, a cytoplasm that fills the interior of the cell, and ribosomes that synthesize proteins....
Like eukaryotic cells, all prokaryotic cells are surrounded by a plasma membrane, have genetic material in the form of single, circular DNA, a cytoplasm that fills the interior of the cell, and ribosomes that synthesize proteins....
122.1K
Microtubules in Cell Motility
3.3K
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
3.3K
Microtubules in Signaling
1.7K
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like structures are present, generally one per cell. These are non-motile cilia in a 9+0 microtubules arrangement, where the central pair of microtubules are absent. The primary cilia arise from the basal body embedded in the cell membrane. Intraflagellar transport (IFT) carries requisite proteins from the cytoplasm to the cilium because the primary...
1.7K
Role of Septins
1.7K
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
1.7K
Symbiosis
27.8K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
27.8K
Eukaryotic Evolution
33.6K
The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
33.6K
