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在婴儿中发现意外胃肠道穿孔的术前临床特征 - - 一项回顾性队列研究
Adinda G H Pijpers1,2,3, Ramon R Gorter1, Laurens D Eeftinck Schattenkerk1
1Department of Pediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Children (Basel, Switzerland)
|May 25, 2024
概括
患有意外胃肠穿孔 (GIP) 的婴儿如果早产或出生体重低,则患小肠穿孔的风险更高. 结肠穿孔需要对赫什普朗格病和囊性纤维化进行查.
科学领域:
- 儿科手术 儿科手术
- 新生儿护理 新生儿护理
- 胃肠病学 胃肠病学
背景情况:
- 婴儿中意外的肺肠意味着胃肠穿孔 (GIP),这是一个关键的手术紧急情况.
- 术前定位GIP具有挑战性,由于小肠和结肠穿孔之间的差异,影响手术策略.
研究的目的:
- 在婴儿中具有意想不到的GIP的术前患者因素的特征.
- 为了区分小肠和结肠的穿孔.
- 为了确定这个群体中GIP的潜在原因.
主要方法:
- 对接受手术的婴儿 (≤6个月) 进行回顾性分析,这些婴儿有意想不到的肺上皮 (1996-2024年).
- 统计分析 (基平方,t测试,邦费罗尼校正) 用于比较穿孔位置.
- 对手术前特征和最终诊断的审查.
主要成果:
- 51名婴儿出现了意想不到的GIP;小肠26个,结肠22个,胃3个穿孔.
- 小肠穿孔与早产,低出生体重 (<1000g),呼吸支和较低的动脉pH相关.
- 结肠穿孔显示了肠道肺炎的更高发病率,并与希尔施普隆病和囊性纤维化有关.
结论:
- 过早出生和低出生体重 (<1000g) 会增加GIP的婴儿小肠穿孔的风险.
- 结肠穿孔需要进一步调查希尔施普隆病和囊性纤维化.
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