探索肥胖,过敏疾病和儿童睡眠呼吸障碍的复杂相互作用
Chiara Voltan1, Francesca Concer1, Luca Pecoraro1
1Pediatric Clinic, Department of Surgery, Dentistry, Gynecology and Pediatrics, University of Verona, 37129 Verona, Italy.
Children (Basel, Switzerland)
|May 25, 2024
概括
儿童肥胖,过敏和睡眠呼吸障碍紧密相关. 共同管理这些疾病对于改善儿童健康状况至关重要,特别是那些患有饮食引起的肥胖症的儿童.
科学领域:
- 儿科健康 儿科健康
- 免疫学 免疫学 免疫学
- 睡眠医学 睡眠医学
背景情况:
- 儿童肥胖影响约20%的儿童,与睡眠呼吸障碍 (SDB) 和喘和过敏性鼻炎等过敏症有关.
- SDB涉及重复的上呼吸道阻塞,导致呼吸暂停和睡眠质量差.
- 过敏和SDB可以创造一个有害的循环,加剧对方的严重程度.
研究的目的:
- 调查儿童群体中肥胖,过敏和SDB之间的相互联系.
- 审查有关饮食诱导与遗传肥胖和过敏疾病之间的关系的现有文献.
- 强调需要对儿童这些相互关联的疾病进行综合管理.
主要方法:
- 通过Medline,PubMed,Scopus和Web of Science数据库识别的研究的叙事审查.
- 搜索从开始到2024年4月进行.
- 分析的重点是儿童肥胖类型,过敏和SDB之间的相关性.
主要成果:
- 在饮食引起的肥胖症中,慢性炎症会加剧过敏和喘/鼻炎. 鼻炎引起的鼻塞可能会使SDB恶化.
- 喘和SDB之间存在双向关系,每一种情况都可能使另一种情况恶化.
- 患有遗传肥胖症的儿童表现出较少的过敏,可能是由于复杂的遗传,免疫和环境因素,尽管机制需要进一步研究.
结论:
- 肥胖,过敏和SDB在儿童中显著相互联系,特别是那些饮食引起的肥胖症.
- 综合评估和管理这些条件对于有效的儿科护理至关重要.
- 需要进一步的研究,以了解遗传肥胖的降低过敏性和潜在机制.
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