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瑞科桑对燃烧口腔综合征的短期镇痛效果:单臂队列研究
Tatsuki Itagaki1, Keisuke Nakamura1, Tougo Tanabe1
1Department of Oral Diagnosis and Medicine, Faculty of Dental Medicine, Hokkaido University, Kita-13 Nishi-7, Kita-ku, Sapporo 060-8586, Japan.
Biomedicines
|May 25, 2024
概括
日本草药Rikkosan在减少口腔炎综合征 (BMS) 患者的疼痛方面显示出短期的有效性. 这项研究发现,在治疗大约四周后,疼痛得分显著下降.
科学领域:
- 口腔医学是指口腔医学.
- 疼痛管理 疼痛管理
- 日本传统医学 (康波)
背景情况:
- 燃烧口腔综合征 (BMS) 是一种慢性口腔疼痛状况,没有确定的标准治疗方法.
- 根据理论,BMS是一种类型的nociplastic疼痛,强调了需要新的治疗方法.
- 坎波医学是一种传统的日本草药系统,为各种疾病提供潜在的替代治疗方法.
研究的目的:
- 为了评估Rikkosan的有效性,一个坎波草药,在管理燃烧口腔综合征的症状.
- 评估Rikkosan对诊断为BMS的患者减轻疼痛的影响.
主要方法:
- 一个单一中心的回顾性研究,涉及20名被诊断患有BMS的患者.
- 患者接受Rikkosan (每天7.5克) 口服大约四周.
- 在治疗前和治疗后使用数值评分表 (NRS) 或视觉模拟表 (VAS) 测量疼痛水平.
主要成果:
- 在Rikkosan治疗一个月后 (-2.1 ± 1.2,p < 0.05) 观察到疼痛得分 (NRS/VAS) 的显著下降.
- 瑞科桑证明了短期效应,平均降低了NRS分数的两级.
- 在研究期间没有报告任何不良事件,这表明了有利的安全性.
结论:
- 瑞科桑可以为患有口腔炎综合征的患者提供有益的短期缓解疼痛的选择.
- 需要进一步的研究来证实这些发现,并探索长期疗效和作用机制.
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