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在怀孕期间活跃和康复的SARS-CoV-2感染后,结肠杆菌乳酸

Paulina Gaweł¹, Błażej Łukianowski², Katarzyna Kościelska-Kasprzak³

¹Department of Neonatology, Wroclaw Medical University, 50-556 Wroclaw, Poland.

|May 25, 2024

概括

患有COVID-19感染的母亲在母乳中的乳酪蛋白 (Lf) 含量更高. 这表明Lf为婴儿提供了针对病毒感染的增强保护.

科学领域:

免疫学免疫学免疫学
人类哺乳期哺乳期
病毒学病毒学

背景情况:

人类母乳中的乳酸 (Lf) 提供了对感染的天生的免疫力.
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 是一个重大的全球健康问题.
了解影响婴儿免疫力的母亲因素在流行病期间至关重要.

研究的目的:

为了量化活跃或过去感染SARS-CoV-2的母亲的乳酪蛋白度.
为了比较感染的母亲,先前感染的母亲和非感染的对照群之间的Lf水平.
评估SARS-CoV-2感染状况和乳母乳中乳酸铁素水平之间的关系.

主要方法:

横截面研究设计. 截面研究设计.
从41名确诊有SARS-CoV-2病史的母亲和28名对照人群中采集的乳盘样本.
酶相关免疫吸收试验 (ELISA) 用于测量Lf度.

主要成果:

与对照人群相比,患有SARS-CoV-2感染的母亲的乳盘Lf度较高.
在分娩时患有活跃SARS-CoV-2感染的母亲中观察到Lf度最高.
在病毒感染和乳酪中的Lf水平之间发现了积极的相关性.

结论:

患有SARS-CoV-2感染的母亲在胆乳中呈现出乳酸的增加.
乳酸氨酸水平升高可能会增强母乳养婴儿对病毒病原体的保护性免疫力.
这一发现强调了乳酸作为婴儿的保护因素的重要性,特别是在母亲感染期间.

关键词:

在 COVID-19 疫情中,这就是SARS-CoV-2病毒.母乳养哺乳期母乳养大奶粉是什么? 大奶粉是什么? 大奶粉是什么?人类母乳是人类的母乳.免疫力是一种免疫力.乳酸铁氨酸 (lactoferrin) 是一种乳酸铁氨酸.

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