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Updated: Jun 25, 2025

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

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分子Chaperonin HSP60:目前的理解和未来的前景

Manish Kumar Singh1,2,3, Yoonhwa Shin1,2, Sunhee Han1,2,4

  • 1Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.

International journal of molecular sciences
|May 25, 2024
PubMed
概括

像热冲击蛋白60 (HSP60) 这样的分子伴侣维持细胞蛋白平衡. HSP60对线粒体健康,蛋白质折叠和细胞应激反应至关重要,在疾病中具有治疗潜力.

关键词:
在HSP60中,HSP60是灭症 (apoptosis) 是一种死亡的过程.癌症 癌症 癌症 癌症 癌症这是一个 chaperonin 陪伴者.这是一种炎症炎症炎症炎症.线粒体中的线粒体.分子陪伴者分子陪伴者蛋白质折叠 蛋白质的折叠

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