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线粒体基因组学证据表明,小体陆地类动物的选择性约束存在于小体陆地类动物中

Xuesong Mei¹, Xibao Wang¹, Xiaoyang Wu¹

¹School of Life Science, Qufu Normal University, Qufu 273165, China.

Animals : an open access journal from MDPI

|May 25, 2024

概括

身体大小影响了 Cetartiodactyla 中的线粒体基因进化. 由于更高的新陈代谢率,小物种在线粒体DNA蛋白质编码基因 (mtDNA PCG) 上面临更强的净化选择,而较大的物种面临更弱的选择.

科学领域:

进化生物学是进化的生物学.
分子进化的分子进化.
基因组学就是基因组学.

背景情况:

身体大小是影响物种之间生理和代谢需求的关键因素.
线粒体基因组蛋白质编码基因 (mtDNA PCG) 对于细胞能量产生至关重要,并且受到进化压力.

研究的目的:

为了研究体型和 mtDNA PCG 在陆地 Cetartiodactyla 的分子演变之间的关系.
为了确定mtDNAPCG的选择压力是否在不同体型的物种之间有所不同.

主要方法:

使用非同义/同义替代率比率 (ω) 的选择压力分析.
遗传学独立对比 (PIC) 来解释进化关系.
对陆地Cetartiodactyla物种的分析.

主要成果:

较小体型的 Cetartiodactyla 对 mtDNA PCG 的 ω 值显著较低,表明更强的净化选择.
mtDNA PCG 的 ω 值与体型正相关 (R2 = 0.162,p = 0.0016).
在几个mtDNAPCG中发现了积极选择的证据,这表明在适应中发挥了作用.

结论:

在Cetartiodactyla中,线粒体基因进化受到身体大小和相关的代谢要求的强烈影响.
净化选择占主导地位,特别是在具有高代谢率的小体物种中.
积极选择可能有助于物种适应不同的环境.

关键词:

这四个是Cetartiodactyla.身体的尺寸身体的大小线粒体基因组的基因组选择性约束选择性的约束

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