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目前的皮状细胞癌的手术前管理:概述

Luigi Della Corte¹, Valeria Cafasso², Maria Chiara Guarino²

¹Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.

|May 25, 2024

概括

本综述考察了皮状细胞癌 (VSCC) 的术前成像,强调MRI和PET作为当前的标准,超声波变得越来越重要. 专家超声波是精确诊断和这种罕见的妇科癌症的分期的关键.

科学领域:

妇科瘤学妇科瘤学
诊断成像诊断成像诊断成像
手术瘤学手术瘤学

背景情况:

阴道状细胞癌 (VSCC) 是最常见的阴道癌类型,是一种罕见的妇科恶性瘤.
精确的手术前分期,包括评估部和淋巴结的参与,对于有效的治疗规划至关重要.
目前的诊断方法包括活检,视镜和先进的成像技术,如超声波 (USG),磁共振成像 (MRI) 和正子发射断层扫描 (PET).

研究的目的:

为了提供一个全面的概述VSCC的当前预操作管理.
评估USG,MRI和PET在评估阴道和淋巴结参与方面的作用和可靠性.
综合关于VSCC分期的各种成像模式的诊断性能的证据.

主要方法:

从2010年到2024年,主要的数据库 (MEDLINE,EMBASE,科学网,Scopus,临床试验.gov,OVID,Cochrane图书馆) 进行了系统的文献搜索.
纳入标准集中在原创文章上,最终评估了17项研究的资格.
数据提取和合成的重点是USG,MRI和PET在VSCC分期中的诊断准确度,灵敏度,特异性和预测值.

主要成果:

卷镜检查显示高度状内皮病变 (vHSIL) 和癌症的适度一致性,对恶性瘤的敏感度高,但特异性低.
对于恶性部病变,PET显示平均标准化摄入值 (SUV) 为8.4,有助于分期和淋巴结评估.
对局部区域透和淋巴结转移的检测,MRI提供了高准确度 (84.8%-86.9%),使用特定的标准,如淋巴结轴尺寸预测恶性瘤. 通过结合皮质厚度和短轴长度测量,提高了USG的准确性.

结论:

虽然MRI和PET被认为是手术前VSCC管理的黄金标准,但超声波越来越有价值,特别是在经验丰富的超声波专家进行时.
成像在精确的瘤分期和指导VSCC治疗决策方面发挥着至关重要的作用.
多学科团队管理对于优化这种罕见的妇科癌症患者的护理至关重要.

关键词:

这就是为什么MRI是MRI.在这里,PET是PET.inguinofemoral 淋巴结的淋巴结的淋巴结的淋巴结超声波超声波是指超声波的使用.vulvar 状细胞癌状细胞癌 vulvoscopy 体镜检查体镜检查体镜检查

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