重新想象结肠直肠癌查:与Aasma Shaukat博士的创新和挑战
Viviana Cortiana1, Muskan Joshi2, Harshal Chorya3
1Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40126 Bologna, Italy.
Cancers
|May 25, 2024
概括
结肠直肠癌 (CRC) 查正在转变,原因是年轻人患结肠直肠癌的病率在上升. 新的基于血液的测试和早期的查年龄显示出早期检测和减少CRC负担的希望.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌 (CRC) 是一个主要的全球健康问题,排名第三最常见的癌症和癌症死亡的第二大原因.
- 在50岁以下的人群中,CRC发病率的增加令人担忧,这促使更新了查指南.
- 目前的选方法有局限性,包括不理想的坚持和早期检测策略的需要.
研究的目的:
- 根据疾病流行病学的变化,审查结直肠癌 (CRC) 查的不断变化的格局.
- 突出新查方式的潜力,包括基于血液的测试和调整的查年龄.
- 讨论医疗保健系统适应这些进步的挑战和机遇.
主要方法:
- 关于CRC查的最新研究和临床指导方针的审查.
- 对早期癌症检测新兴技术的分析,包括利用人工智能和机器学习的基于血液的测试.
- 考虑新的查技术的医疗保险覆盖标准.
主要成果:
- 美国癌症协会现在建议从45岁开始对平均风险个体进行CRC查.
- 基于血液的测试显示了早期CRC检测具有高灵敏度和特异性的承诺,等待FDA批准和指导方针的纳入.
- 目前正在进行的临床试验和多种癌症检测测试 (例如GRAIL) 是显著的进步.
结论:
- 降低查年龄和将基于血液的测试与现有方法相结合,可以显著降低CRC负担.
- 解决新查技术的可访问性和负担能力对于广泛采用至关重要.
- 医疗保健系统必须适应变化的结直肠癌流行病学模式.
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