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Updated: Jun 25, 2025

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells
08:11

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells

Published on: August 7, 2021

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通过PRMT5依赖的对称二甲基化调节RORα稳定性

Gaofeng Xiong1,2,3,4, Brynne Obringer5, Austen Jones5

  • 1Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.

Cancers
|May 25, 2024
PubMed
概括

蛋白质氨酸N-甲基转移酶5 (PRMT5) 稳定了与视网酸受体相关的孤儿受体α (RORα) 蛋白. PRMT5调节RORα的稳定性,影响乳腺癌细胞的入侵和迁移.

关键词:
在PRMT5中,我们使用了PRMT5.RORα 是一个RORα.哺乳动物上皮细胞甲基化疗法 甲基化疗法稳定的稳定性 稳定的稳定性

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