肺栓塞的结果与没有缺血性中风
Karsten Keller1,2,3, Volker H Schmitt1,4, Omar Hahad1,4
1Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.
Journal of clinical medicine
|May 25, 2024
概括
肺栓塞 (PE) 患有缺血性中风的患者面临更高的死亡率. 带有心脏隔膜缺陷的深静脉血栓和心房动是PE患者中风风险的关键因素. 系统性血栓溶解改善了CPR接受中风的PE患者的生存率.
科学领域:
- 心血管医学 心血管医学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 缺血性中风和肺栓塞 (PE) 是导致心血管死亡的主要原因.
- 关于急性PE患者缺血性中风风险因素的数据有限.
- 了解这些风险因素对于改善患者的治疗结果至关重要.
研究的目的:
- 在急性肺栓塞住院患者中确定缺血性中风的危险因素.
- 分析缺血性中风对PE患者住院死亡率的影响.
- 评估系统性血栓溶解在PE患有缺血性中风的患者进行心肺复苏的有效性.
主要方法:
- 2011-2014年德国全国住院患者样本数据的分析.
- 包括诊断为PE的患者 (ICD代码I26).
- 在患有缺血性中风和没有缺血性中风的PE患者中分层和比较 (ICD代码I63).
主要成果:
- 在346,586名PE患者中,6,704名 (1.9%) 也患有缺血性中风.
- 患有缺血性中风的PE患者在医院内死亡率明显较高 (28.9%与14.5%相比).
- 在PE患者中,中风的独立风险因素包括心脏隔膜缺陷的DVT和心房动/动. 系统性血栓溶解改善了CPR接受中风的PE患者的生存率.
结论:
- 缺血性中风显著恶化肺栓塞患者的生存率.
- 深静脉血栓 (DVT) 与心脏隔膜缺陷和心房的结合是PE患者缺血性中风的强有力的独立风险因素.
- 系统性血栓溶解与经历过缺血性中风并需要心肺复苏 (CPR) 的PE患者的生存率提高有关.
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