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眼部生物特征百分位曲线及其与印度儿童近视发展的关系
Aparna Gopalakrishnan1,2,3, Viswanathan Sivaraman1, Jameel Rizwana Hussaindeen1
1Myopia Clinic, Sankara Nethralaya, Unit of Medical Research Foundation, Chennai 600006, India.
Journal of clinical medicine
|May 25, 2024
概括
这项研究为6至12岁的印度儿童提供了眼部生物识别百分位数值,为监测近视发展和识别有风险的个体建立了基准.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 生物识别仪表是如何使用的
背景情况:
- 近视的患病率在全球范围内不断增加,特别是在儿童中.
- 建立规范性的眼部生物识别数据对于早期检测和干预至关重要.
- 之前的研究缺乏印度儿科人口的特定百分位数值.
研究的目的:
- 为6-12岁的印度儿童生成眼部生物识别百分位值.
- 评估这些百分位数在预测近视发展中的有用性.
- 帮助儿童近视的监测和早期干预策略.
主要方法:
- 长度研究 (Sankara Nethralaya 泰米尔纳德邦精近视研究 - STEM).
- 测量了4514名儿童 (一年级,四年级,六年级) 的客观折射和眼部生物测量 (轴长,角膜曲率).
- 生成百分比曲线;使用随访数据分析近视发作的预测值.
主要成果:
- 在研究队列中,基线近视患病率为11.7%.
- 轴长 (AL) 和AL/角膜曲率 (AL/CR) 的比率显示出与年龄和年级的显著线性趋势.
- AL/CR比率百分点 (第50个,第75个) 显示了近视发病的良好预测值 (AUC 0.72-0.79);联合AL和百分点转移改善了AUC至0.83.
结论:
- 该研究为6-12岁的印度儿童提供了第一个特定的眼部生物识别百分位数值.
- 这些百分值是监测眼睛生长和识别近视高风险儿童的宝贵工具.
- 这些发现支持使用眼部生物识别百分位数来主动管理儿科患者的近视.
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