在重度肥胖的住院患者中 Sarcopenia 的患病率:一项观察性研究
Raffaella Cancello1, Ettore Brenna2, Davide Soranna2
1Obesity Unit, Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, 20121 Milan, Italy.
Journal of clinical medicine
|May 25, 2024
概括
肥胖症 (SO) 影响11.48%的严重肥胖患者,特别是女性和70岁以上的患者. 这种以多余的脂肪和肌肉缺陷为特征的疾病与BMI无关,而是与年龄和性别有关.
科学领域:
- 老年学是指老年学的学科.
- 肥胖医学 肥胖医学
- 临床营养学 临床营养学
背景情况:
- 肥胖症 (SO) 结合了多余的脂肪与肌肉质量和功能的减少.
- 目前的ESPEN/EASO诊断标准需要在严重肥胖的人群中进行验证.
- 在严重肥胖的住院患者中SO的患病率需要确定,考虑到人口统计学和临床因素.
研究的目的:
- 在一大批患有严重肥胖的住院患者中确定形肥胖 (SO) 的患病率.
- 分析SO患病率与性别,年龄,BMI和并发症的关联.
- 为了确定这个患者群体中SO的风险因素.
主要方法:
- 生物电阻分析 (BIA) 和手握强度 (HS) 评估了身体组成和肌肉功能.
- 心理总体幸福指数 (QoL) 评估了生活质量.
- 分析了3858名年龄在18-90岁之间的住院患者 (BMI ≥30 kg/m2) 的数据.
主要成果:
- 这种疾病的患病率为11.48%,女性 (12.39%) 和70岁以上的人 (27%) 的患病率更高.
- 肌肉质量缺陷几乎是普遍的 (99.71%),而力量缺陷影响了11.51%.
- 在BMI类别中,SO的患病率没有显著差异 (30-40 vs.>40 kg/m2),并且与"低"的QOL有关.
结论:
- 根据ESPEN/EASO标准,在严重肥胖的住院患者中,SO的患病率为11.48%.
- 年龄 (>70岁) 和女性性别是SO的重要决定因素,独立于BMI.
- 整合疾病分期和QoL查可以提高SO风险识别.
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