长期旅行者和最近抵达的移民中多药耐药微生物殖民的流行率和危险因素
Víctor Monsálvez1, Paula Bierge2,3, María Luisa Machado1
1Infectious Diseases Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, 08208 Sabadell, Spain.
Microorganisms
|May 25, 2024
概括
国际旅行可能会导致旅行者和移民体内多药耐药 (MDR) 细菌的殖民. 以前的医院治疗是这种殖民的主要风险因素.
科学领域:
- 微生物学 微生物学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 多药耐药 (MDR) 细菌构成了严重的全球健康威胁.
- 国际旅行是MDR细菌传播的潜在途径.
- 无症状的旅行者殖民可以促进细菌的传播.
研究的目的:
- 评估长期旅行者和最近移民中MDR细菌殖民的风险.
- 在这些人群中确定与MDR细菌殖民相关的风险因素.
- 调查国际旅行在MDR细菌传播中的作用.
主要方法:
- 从2018年11月到2022年2月进行的横截面研究.
- 从旅行者和移民中采集喉和直肠拭子.
- 使用染色介质和MALDI-TOF-MS识别细菌,通过分子生物学技术确定耐药性机制.
主要成果:
- 11.5%的参与者 (移民和旅行者) 显示了MDR细菌的直肠殖民.
- 最常见的分离物是扩展光谱β-乳糖酶 (ESBL),产生大肠杆菌 (CTX-M-15).
- 没有检测到MRSA或生产卡巴酶的肠杆菌菌的殖民.
结论:
- 对于移民和长期旅行者来说,MDR细菌殖民的风险是相似的.
- 以前的医院治疗是MDR细菌殖民的唯一独立风险因素.
- 国际旅行,特别是在先前在医院暴露的个体中,需要注意MDR细菌监测.
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