在免疫能力强的患者中引起的血流感染Erysipelothrix rhusiopathiae
Irene Mileto1,2, Cristina Merla1, Marta Corbella1
1Department of Microbiology & Virology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Microorganisms
|May 25, 2024
概括
动物病原体Erysipelothrix rhusiopathiae可能会导致严重的感染. 这一案例突出了它在免疫能力强的个体中罕见发生的细菌病,强调了血液培养的重要性.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 埃里西佩洛特里克斯 (Erysipelothrix rhusiopathiae) 是一种格拉姆阳性细菌和动物性病原体,主要在职业群体中引起 erysipeloid.
- 感染通常表现为局部或普遍的皮肤形式,或败血症形式.
- 诊断可能是具有挑战性的,因为各种症状和严重的系统并发症的潜力,如内心炎.
研究的目的:
- 报告从一个免疫能力强的患者中分离和描述Erysipelothrix rhusiopathiae.
- 突出诊断挑战和血液培养在识别E. rhusiopathiae bacteremia中的重要性.
- 为临床隔离物提供抗微生物敏感性数据.
主要方法:
- 从血液培养物中分离和鉴定Erysipelothrix rhusiopathiae.
- 使用EUCAST断点 (PK-PD) 解释的抗微生物敏感性测试.
- 一个56岁的肥胖,免疫能力强的男性的临床病例报告.
主要成果:
- 从血液培养物中成功分离了Erysipelothrix rhusiopathiae.
- 确定的菌株对所有测试的抗生素都敏感,但对万科米辛有内在的耐药性.
- 由E. rhusiopathiae引起的细菌病在免疫能力强的患者中得到证实,这是罕见的.
结论:
- 血液培养对于诊断Erysipelothrix rhusiopathiae bacteremia至关重要,特别是在免疫能力强的个体中.
- 由于病原体与其他临床疾病的相似性,可能存在误诊.
- 这一案例强调了在感染的差异诊断中考虑E. rhusiopathiae的重要性,即使在免疫能力强的宿主中也是如此.
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