维生素B1缺乏症通过偶然检测出高乳糖血症来确定:一个病例报告
Yuki Omura1, Koshi Ota2, Akira Takasu2
1Department of General Medicine, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-machi, Takatsuki City 596-8686, Osaka, Japan.
Medicina (Kaunas, Lithuania)
|May 25, 2024
概括
无法解释的高乳糖血症可能表明维生素B1缺乏,即使在发达国家. 在高危人群中通过乳酸水平查及早检测可以预防韦尔尼克病.
科学领域:
- 营养神经科学 营养神经科学
- 临床生物化学 临床生物化学
- 内部医学 内部医学
背景情况:
- 维生素B1缺乏会导致严重的神经和心血管问题,包括韦尼克脑病.
- 维尼克脑病症的症状,如眼,精神状态变化和心动缺陷,并不总是存在,从而使诊断复杂化.
- 亚临床维生素B1缺乏症可以在没有明显症状的情况下发展为严重的并发症.
研究的目的:
- 为了强调在患者中考虑维生素B1缺乏症的重要性,无法解释的高乳糖血症.
- 强调早期检测和干预,以预防韦尼克脑病变.
- 建议在有风险人群中主动测量乳酸盐水平.
主要方法:
- 一个65岁的男性的病例介绍,偶尔检测到高乳酸血症.
- 调查显示,维生素B1含量低,酸盐含量高.
- 治疗包括饮食调整和补充剂.
主要成果:
- 超乳糖血症被确定为无症状维生素B1缺乏症的标志物,患者出现.
- 证实了低维生素B1水平和高的酸盐水平.
- 随着维生素B1补充和饮食改变,症状显著改善.
结论:
- 无法解释的高乳糖血症可能表明维生素B1缺乏,即使在高收入国家.
- 早期诊断维生素B1缺乏症对于防止进展为韦尼克脑病变至关重要.
- 风险人群中乳酸盐水平的查可以帮助早期诊断并改善患者的治疗结果.
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