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在真实生活中预测鼻瘤的预后

Giancarlo Pecorari¹, Gian Marco Motatto¹, Federica Piazza¹

¹Division of Otorhinolaryngology, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.

Journal of personalized medicine

|May 25, 2024

概括

诊断鼻癌晚期影响预后. 多模式治疗改善了生存率,但早期诊断对于鼻癌患者的更好的结果至关重要.

科学领域:

在瘤学瘤学.
耳鼻喉科耳鼻喉科耳鼻喉科
癌症研究癌症研究

背景情况:

鼻癌带来了诊断挑战和多样化的组织学,尽管有多学科的护理,但往往导致预后不佳.
对鼻癌病例的回顾性分析侧重于组织学和现实世界的预后.

研究的目的:

评估患有鼻癌的患者的临床特征,生存结果和预后因素.
分析组织学对鼻癌预后的影响.

主要方法:

对51名连续的鼻癌患者进行了回顾性研究.
使用卡普兰-梅尔曲线计算总生存率 (OS),无病生存率 (DFS) 和疾病特异性生存率 (DSS).
考克斯多变量回归分析,以评估年龄,阶段和组织学对生存的影响.

主要成果:

状细胞癌是最常见的组织学,其次是腺癌.
全球五年运行周期为54.58%,DFS为29.56%,DSS为74.57%.
晚期 (43个月) 与早期 (74个月) 癌症的中位寿命显著较短;然而,在多变量分析中,年龄,阶段和组织学并没有显著影响生存结果.

结论:

晚期诊断和不良预后仍然是鼻癌的重大挑战.
多模式治疗实现了全球5年生存率略高于50%.
提高早期诊断率对于改善鼻癌患者的预后至关重要.

关键词:

鼻的瘤鼻的瘤在现实生活中预测预后.鼻癌是一种鼻癌.幸存率幸存率生存率

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