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Updated: Jun 25, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

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瓜核酸交换因子DOCK11在HBV进入和在肝细胞中的持久性方面所起的作用

Ying-Yi Li1, Kazuhisa Murai2, Junyan Lyu2

  • 1Department of Gastroenterology, Kanazawa University Graduate School of Medicine, 13-1, Takaramachi, Kanazawa 920-8640, Japan.

Viruses
|May 25, 2024
PubMed
概括

细胞动力学11分辨器 (DOCK11) 蛋白质通过使病毒DNA转录和复制成为可能,有助于乙型肝炎病毒 (HBV) 的持久性. 用10M-D42AN抑制DOCK11抑制HBV,为慢性乙型肝炎提供了潜在的治疗策略.

关键词:
在 DOCK11 里面,你会看到 DOCK11.cccDNA 持续性 持续性乙型肝炎病毒的感染.逆行性贩运是逆行性的贩运.

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