相关实验视频

Updated: Jun 25, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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树突细胞中的β-catenin通过免疫检查点分子Tim-3负面调节CD8T细胞免疫反应

Chunmei Fu1,2,3, Jie Wang1,2,3, Tianle Ma4

  • 1Center for Cutaneous Biology and Immunology, Department of Dermatology, Henry Ford Health, Detroit, MI 48202, USA.

Vaccines
|May 25, 2024
PubMed
概括

在树突细胞中激活β-catenin可调节Tim-3,抑制CD8 T细胞免疫力. 用DC疫苗和anti-Tim-3疗法准这种β-catenin/Tim-3轴可以增强抗瘤反应.

关键词:
CD8 T 细胞免疫力蒂姆-3的时间.基于树突细胞的疫苗.免疫检查点封锁封锁这是一种β-catenin.

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