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Updated: Jun 25, 2025

Efficient Transcriptionally Controlled Plasmid Expression System for Investigation of the Stability of mRNA Transcripts in Primary Alveolar Epithelial Cells
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结构修改和优化以抑制TGF-β诱导的EMT活动为导向的超氧化物在膜上皮细胞中的结构修改和优化

Ziye Gao1, Mengzhen Xu1, Chuanguo Liu2

  • 1Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.

Pharmaceuticals (Basel, Switzerland)
|May 25, 2024
PubMed
概括

一种新型的超酸衍生物Z6有效地逆转上皮层-介质细胞过渡 (EMT) 并抑制肺纤维化模型中的细胞迁移. 这种化合物对开发肺纤维化新疗法充满希望.

关键词:
在TGF-β1中.凝聚力和迁移 凝聚力和迁移细胞形态 细胞形态表皮介酶过渡 (EMT) 发生.高素的衍生品高素的衍生品肺部纤维化 肺部纤维化

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相关概念视频

TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
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