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对急性医院患者的点患病率调查,这些患者难以吞固体口服剂量形式
Anne Harnett1,2, Stephen Byrne2, Jennifer O'Connor2
1University Hospital Limerick, Dooradoyle, V94 F858 Limerick, Ireland.
大约15.4%的医院患者有吞困难. 修改固体口服药物,通常是通过粉碎,导致严重的注射错误,危及患者的安全.
科学领域:
- 药房 药房 药房 药房
- 临床药房 临床药房
- 患者安全 患者安全
背景情况:
- 固体口服药物安全地给患有吞困难的住院患者提供了重大挑战.
- 缺食症影响到急性医院人口的很大一部分,需要谨慎的药物管理.
研究的目的:
- 确定急性住院患者中难以吞固体口服剂型的患病率.
- 研究修改固体口服剂型的方法,这些修改的适当性,以及相关的患者共发病症.
主要方法:
- 在三个不同的时间点进行了点患病率研究.
- 收集的数据包括吞困难的患病率,修改技术,修改适当性和患者的并发症.
主要成果:
- 在急性住院患者中,观察到吞困难的平均患病率为15.4%.
- 在患有吞困难和没有肠道输液管的患者中,6.0%接受了至少一种改性药物,压碎是最常见的方法 (14.4%的注射错误率).
- 高血压是最常见的并发症;只有5.5%的患有吞困难的患者发现了吞障碍.
结论:
- 不适当地修改固体口服剂型可能会对患者造成伤害.
- 包括查工具在内的积极策略至关重要,以识别患有吞困难的住院患者,并减轻与药物修改相关的风险.
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