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来自植物的类似囊泡的纳米粒子:下一代药物输送纳米平台
Xiaoxia Wang1, Congling Xin2, Yu Zhou3
1Key Laboratory of Smart Drug Delivery (Ministry of Education), Minhang Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 201203, China.
Pharmaceutics
|May 25, 2024
概括
来自植物的囊泡状纳米颗粒 (PDVLNs) 显示出作为安全和成本效益的药物输送系统 (DDS) 的承诺. 本综述探讨了它们作为下一代治疗纳米平台的潜力,用于治疗各种疾病.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 来自植物的天然生物活性化合物对于治疗癌症,慢性炎症和其他慢性疾病等疾病具有重要的临床意义.
- 由于其有利的特性,来自植物的囊泡状纳米粒子 (PDVLNs) 正成为药物递送系统 (DDS) 的有希望的候选者.
研究的目的:
- 综合审查和巩固PDVLNs作为下一代药物输送纳米平台的当前发展.
- 为读者提供PDVLN生物发生,特征,组成,管理和应用的概述.
- 讨论PDVLNs在治疗环境中的优点和局限性.
主要方法:
- 文献综述和现有关于植物状纳米颗粒 (PDVLNs) 的研究综合.
- 分析着重于PDVLN生物发生,表征和药物输送应用的研究.
- 评估PDVLNs治疗用途的优点和局限性.
主要成果:
- PDVLN提供了具有成本效益的生产,无毒性,无免疫性和出色的生物相容性.
- 目前的研究突出了PDVLNs在各种疾病的药物输送中的多样化应用.
- PDVLNs为传统药物输送系统提供了一个可行的替代方案.
结论:
- PDVLNs准备成为下一代药物输送纳米平台.
- 它们的固有特性使它们成为未来医疗应用的有价值的治疗方式.
- 预计进一步的研究和开发将加强PDVLNs在临床实践中的作用.
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