植物酸盐摄入量与心血管疾病风险和死亡率之间的关联:系统性审查
Loucas Tan1, Libby Stagg1, Emily Hanlon1
1School of Biomedical, Nutritional & Sports Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Nutrients
|May 25, 2024
概括
吃富含酸盐的蔬菜与降低心血管疾病 (CVD) 风险有关. 这项审查发现,蔬菜酸盐摄入量可能会降低心血管疾病发病率和死亡率,在适度消费水平下,益处可能会平稳.
科学领域:
- 心血管科学 心血管科学
- 营养流行病学 营养流行病学
- 饮食中酸盐研究
背景情况:
- 富含酸盐的蔬菜增强了氧化 (NO) 的生物可用性,积极影响血压和内皮功能.
- 这些生理效应表明,降低心血管疾病 (CVD) 风险和死亡率的潜在好处.
- 了解饮食中的植物酸盐与心血管疾病结果之间的关联对于公共卫生建议至关重要.
研究的目的:
- 系统地审查关于习惯性植物酸盐摄入量与心血管疾病发病率或死亡率之间的关联的观察研究.
- 探索影响蔬菜酸盐摄入量与心血管疾病结局之间的关系的潜在缓解因素.
- 综合当前关于蔬菜中酸盐在心血管健康中的作用的证据.
主要方法:
- 对七个主要科学数据库进行了全面的系统审查.
- 包括的研究量化了植物酸盐摄入量,并评估了成年人 (18岁以上) 的心血管疾病发病率或死亡率.
- 五项63,155名参与者的观察性研究符合资格标准.
主要成果:
- 在蔬菜酸盐摄入量和大多数心血管疾病结果之间观察到一个反向关联.
- 有证据表明,潜在的上限效应,风险降低在适度摄入水平上停滞不前.
- 包含的研究显示偏差风险较低,加强了研究结果.
结论:
- 习惯性摄入植物酸盐在减轻心血管疾病风险和死亡率方面发挥了有希望的作用.
- 通过随机对照试验进行进一步的调查是有必要的,以确认这些关联.
- 来自蔬菜的食酸盐可能是预防心血管疾病的可改变因素.
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