儿童时期的逆境和怀孕的时间在预先概念队列中
Sharonda M Lovett1, Olivia R Orta1, Renée Boynton-Jarrett2
1Department of Epidemiology, Boston University School of Public Health, Boston, MA 02118, United States.
American journal of epidemiology
|May 25, 2024
概括
童年逆境可能会降低怀孕的可能性. 然而,强大的童年社会支持可以稍微缓解这些对生育能力的负面影响,即每周期怀孕的机会.
科学领域:
- 生殖流行病学 生殖流行病学
- 健康中的心理社会因素
背景情况:
- 童年逆境与不利的健康结果有关.
- 它对生育能力的影响,每周期的受孕概率,需要进一步调查.
- 儿童社会支持的修改作用尚未完全理解.
研究的目的:
- 检查童年逆境与生育能力之间的关联.
- 确定儿童时期的社会支持是否会改变这种关联.
主要方法:
- 预见性预孕队列研究 (在线妊娠研究,PRESTO) 涉及6318名女性参与者 (21-45岁).
- 通过关于不良童年经历 (ACE) 和社会支持 (社会网络指数 (SNI)) 的问卷收集的数据.
- 使用比例概率回归模型来计算生育率 (FRs),调整以考虑混因素.
主要成果:
- 增加的ACE分数与降低的生育能力有关 (FR分别为0.91和0.84对于1-3和≥4个ACE).
- 对于≥4个ACE,高的童年社会支持 (SNI ≥4) 与低的社会支持 (FR 0.78) 相比,对生育能力的减少较小 (FR 0.86).
- 童年社会支持似乎缓冲了逆境对受孕概率的负面影响.
结论:
- 儿童时期的逆境与生育能力的降低有关.
- 高的童年社会支持可以减轻逆境对怀孕概率的负面影响.
- 研究结果支持童年经历和社会支持网络对健康的长期影响.
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