棕色瘤:对26例病例的回顾性分析
Mustafa Onur Karaca1, Mustafa Özyıldıran2, Merve Dursun Savran1
1Department of Orthopedics and Traumatology, Ankara University, Ankara, Turkey.
Archives of orthopaedic and trauma surgery
|May 25, 2024
概括
棕色瘤,来自甲状腺功能障碍症的反应性骨损伤,被研究了34年. 大多数患者患有原发性副甲状腺功能障碍;治疗涉及手术或保守管理,没有观察到复发.
科学领域:
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
- 病理学 病理学 病理学
背景情况:
- 棕色瘤是一种罕见的,非新发性骨解病变,是由甲状腺功能障碍症引起的骨复苏引起的.
- 这些病变通常与一次性或二次性甲状腺功能障碍症有关.
研究的目的:
- 为了回顾34年的棕色瘤机构经验.
- 分析棕色瘤的临床表现,诊断和管理.
主要方法:
- 在1988年5月至2020年10月期间,连续26名被诊断患有棕色瘤的患者的回顾性分析.
- 收集的数据包括患者人口统计,临床表现,诊断结果,治疗方法和后续结果.
主要成果:
- 该研究包括26名患者 (65.4%男性,34.6%女性),平均年龄为41.6岁.
- 常见的症状包括局部骨疼痛 (50.0%) 和病理骨折 (26.9%).
- 大多数患者 (88.5%) 患有原发性副甲状腺功能障碍. 病变通常在骨盆,大腿骨和肋骨中发现. 治疗涉及21名患者的骨科手术 (切除,骨,骨移植) 和5名患者的保守管理,没有观察到复发.
结论:
- 棕色瘤的诊断依赖于临床怀疑,需要咨询内分泌学和整体外科.
- 为了有效治疗棕色瘤,必须采用多学科的方法.
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