在家用灰尘中与8个受影响社区的生物监测数据和粉和多粉基物质 (PFAS) 暴露的联系
Jeffrey M Minucci1, Nicole M DeLuca1, James T Durant2
1U.S. EPA, Office of Research and Development, Center for Public Health and Environmental Assessment, United States.
Environment international
|May 25, 2024
概括
靠近PFAS污染地的居民可能通过家用灰尘而增加暴露,而不仅仅是饮用水. 室内因素,如清洁习惯和家庭特征影响这些水平,影响整体身体负担.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 和多基基物质 (PFAS) 是常见的工业化学品,具有已知的不良健康影响.
- 靠近PFAS制造或使用地点的社区面临着高暴露风险,主要是通过污染的饮用水.
- 对于其他暴露途径的了解有限,例如通过室内尘埃暴露的住宅暴露.
研究的目的:
- 调查血清PFAS水平和室内灰尘PFAS水平在有记录饮用水污染的社区之间的关联.
- 探索家庭潜在的PFAS暴露来源,并确定与高尘 PFAS水平相关的人口,行为和住房因素.
主要方法:
- 来自8个受水膜形成泡 (AFFF) 污染影响的美国社区的配对血清和室内灰尘样本的分析.
- 统计分析以确定血清和粉尘PFAS之间的关联,控制地点和参与者的年龄.
- 评估暴露问卷数据以确定与粉尘PFAS度相关的因素.
主要成果:
- 在分析的七种PFAS中,三种PFAS的血清PFAS水平与室内灰尘PFAS水平显著相关.
- 增加的粉尘PFAS与血清PFAS概况的转变相关,这表明家庭来源.
- 年龄较大,居住时间较长,清洁频率较低,使用耐污染产品和地毯客厅与较高的PFAS粉尘水平有关.
结论:
- 通过家用灰尘对PFAS的住宅暴露有助于整体暴露和身体负担,即使在有污染饮用水的地区.
- 人口,行为和住房因素显著影响室内PFAS暴露的程度.
- 对室内暴露途径的进一步研究对于全面的风险评估和缓解策略至关重要.
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