低握力与慢性病患者的高回声性有关:一个试点,横截面和探索性研究
Jéssica Ferreira Mayrink Ivo1, Tatyanne L N Gomes1, Lara G Mainardi1
1Post-Graduation in Nutrition and Health, Faculty of Nutrition, Federal University of Goias, Goiânia, GO, Brazil.
Revista espanola de geriatria y gerontologia
|May 25, 2024
概括
三脚臂肌的超声测量,特别是回声效应 (EI),与非透析依赖慢性病 (nd-CKD) 患者的手握强度 (HGS) 有关. 在这个人群中,EI对诊断低HGS很敏感.
科学领域:
- 肌肉骨超声波 肌肉骨超声波
- 腎臟病學 (nephrology) 是一種醫學.
- 生物医学工程 生物医学工程
背景情况:
- 手握强度 (HGS) 是肌肉功能和整体健康的关键指标.
- 在慢性病 (CKD) 患者中,减少HGS是常见的,影响预后.
- 非透析依赖性CKD (nd-CKD) 患者可能受益于评估肌肉健康的非侵入性方法.
研究的目的:
- 为了评估三腕 (TB) 肌肉超声波测量和HGS在nd-CKD患者之间的关联.
- 为了确定结核病超声波的敏感性来诊断低HGS.
- 探索结核病超声波参数在评估nd-CKD肌肉功能的实用性.
主要方法:
- 一个横截面的探索性试点研究,涉及42nd-CKD成年人.
- 三臂 (TB) 肌肉超声波 (US) 评估了肌肉厚度 (MT),回声性 (EI),横截面积 (CSA),笔纹角 (PA) 和带长度 (Lf).
- 手握强度 (HGS) 被测量并将其正常化为体重指数 (BMI);低HGS以性别和年龄特定百分比来定义. 用于诊断准确性的ROC分析.
主要成果:
- 低HGS组与充足的HGS组相比,表现出更高的脂肪质量,更大的TB肌肉PA,并增加了EI.
- 增加的EI与减少的HGS显著相关,即使经过性别,年龄和脂肪质量调整 (p=0.011).
- 胸三肌的回声性 (EI) 显示出中度的诊断准确性 (AUC=0.730) 和86.9%的灵敏度来检测低HGS.
结论:
- 在nd-CKD患者中,三腕肌的回声性 (EI) 是与手握强度 (HGS) 相关的最显著的超声测量.
- 胸三肌的回声性 (EI) 是唯一的超声波参数,在这个队列中被发现对诊断低HGS敏感.
- 对三脚臂肌的超声波评估提供了一个有希望的,敏感的工具,用于评估nd-CKD患者的肌肉力量缺陷.
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