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Updated: Jun 25, 2025

Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing
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Generating Transposon Insertion Libraries in Gram-Negative Bacteria for High-Throughput Sequencing

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作为抗生素增强剂的arg-biodynamers通过与格拉姆阴性外膜脂多聚糖化合物相互作用

Mohamed A M Kamal1, Justine Bassil1, Brigitta Loretz2

  • 1Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarland University, 66123 Saarbrücken, Germany; Saarland University, Department of Pharmacy, 66123 Saarbrücken, Germany.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|May 25, 2024
PubMed
概括

新型基于的生物动力学体显示了对格兰负细菌膜的增强向,改善了抗生素的输送和克服耐药性. 这些可生物降解的聚合物降低了毒性,同时增强了对抗菌性细菌的抗菌活性.

关键词:
细菌的生物利用性 细菌的生物利用性细菌细胞的外是细菌细胞的外.可生物降解的聚合物.膜活性聚合物 膜活性聚合物二级结构是次要结构.超分子相互作用

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