对大血管封闭的机械血栓切除术后的并发症负担和结果:回顾性分析
Satoru Fujiwara1, Yoshinori Matsuoka2, Nobuyuki Ohara1
1Department of Neurology, Kobe City Medical Center General Hospital, Kobe, Japan.
概括
在接受机械血栓切除术的急性缺血性中风患者中,高并发症负担与较差的神经结果和增加出血风险有关. 查尔森并发症指数 (CCI) 可以预测预后.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
背景情况:
- 患有急性缺血性中风 (AIS) 的患者通常存在多种先前存在的健康状况 (并发症).
- 这种并发症负担对AIS机械血栓切除术 (MT) 后的结果的影响尚不清楚.
研究的目的:
- 调查AIS患者中先前存在的并发症负担是否预测MT后的临床结果.
- 评估查尔森并发症指数 (CCI) 在预测结果中的有用性.
主要方法:
- 对388名社区发病的AIS患者进行了回顾性队列研究,他们接受了MT.
- 使用查尔森并发症指数 (CCI) 评估并发症负担,将患者分为高CCI (≥3) 和低CCI (<3) 组.
- 主要结局:90天后神经学结果良好 (修改的兰金度表0-2). 二次结果:90天死亡率和出血并发症.
主要成果:
- 22.2%的患者具有高CCI.
- 高CCI与实现良好的神经结果的几率明显降低 (aOR 0.26).
- 在高CCI组中,有症状的内出血更频繁 (14.0%vs4.6%).
结论:
- 通过CCI测量的并发症负担与AIS患者的MT后的临床结果有显著的相关性.
- CCI显示出其作为一种简单而有价值的工具,用于预测这种患者群体的神经预后的潜力.
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