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花的总糖化物通过阻断STING-IRF3相互作用来缓解cGAS-STING介导的疾病

Ye Xiu1, Sihao Wang2, Ping Zhang3

  • 1School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.

Chinese journal of natural medicines
|May 25, 2024
PubMed
概括

的总糖化物 (TGP) 抑制cGAS-STING通路,减少炎症介质和IRF3酸化. 通过准这种途径,TGP显示出对炎症和自身免疫性疾病的治疗潜力.

关键词:
炎症 炎症是一种炎症.在LPS/D-GalNN中使用.这是一种STING抑制剂.盖奥尼的葡萄糖类总量在cGAS-STING路径中.

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