在从COVID-19中恢复过来的受试者中持续的运动呼吸系统低效率. 纵向数据分析 34 个月 后 免费 后
Gianluigi Dorelli1,2, Giulia Sartori3, Giulia Fasoli1
1School of Medicine in Sports and Exercise, University of Verona, Verona, Italy.
BMC pulmonary medicine
|May 25, 2024
概括
感染后34个月后,在16%的COVID-19后患者中发现了持续的运动呼吸系统低效率 (EVin). 这种情况与较差的心肺呼吸反应相关,突出显示了长期随访的必要性.
科学领域:
- 心血管呼吸系统生理学
- 传染病研究 传染病研究
- 肺部康复治疗 肺部康复治疗
背景情况:
- 感染SARS-CoV-2的长期健康后果越来越令人担忧.
- 运动呼吸系统低效率 (EVin) 是一种潜在的长期后果,影响呼吸和心血管健康.
- 了解COVID-19后持续性EVin对于患者管理至关重要.
研究的目的:
- 评估COVID-19后34个月内长期存在的EV.
- 调查持续的EVin与心脏呼吸系统健康之间的联系.
- 探索呼吸器低效率与运动反应之间的相关性.
主要方法:
- 一项涉及32名COVID后患者的纵向研究.
- 在出院后6个月和34个月进行了两次心肺运动测试 (CPET).
- 测量的主要参数包括V̇O2峰值,PETCO2,OUES和DLCO.
主要成果:
- 16%的患者在34个月后表现出持续的EVin (pEVin).
- 与EVef. pEV受试者相比,pEV受试者表现出高通风 (较低的PETCO2) 和缺乏心肺功能改善的情况.
- 在高通风,氧脉冲和OUES之间发现了显著的相关性.
结论:
- 一个值得注意的COVID后患者子组经历了持续的EVin.
- 持续的EVin与运动期间心血管反应的改变有关.
- 长期的随访和对持续的呼吸系统低效率的进一步研究在临床上很重要.
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