伴随性疾病对慢性阻塞性肺病患者长期机械呼吸的影响
Kuang-Ming Liao1,2, Hsueh-Yi Lu3, Chung-Yu Chen4
1Department of Internal Medicine, Chi Mei Medical Center, Chiali, Taiwan.
伴随性疾病显著增加了慢性阻塞性肺病 (COPD) 患者长期机械呼吸 (PMV) 的风险. 这些情况,以及年龄和性别,是COPD患者PMV发生的关键因素.
科学领域:
- 肺部医学 肺部医学
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 患有急性呼吸衰竭的慢性阻塞性肺病 (COPD) 患者具有很高的风险 (约. 10%) 长时间的机械通风 (PMV,>21天).
- PMV与不利的结果有关.
- 之前的研究发现,年龄较大和COPD严重程度是PMV风险因素.
研究的目的:
- 研究伴随性疾病对COPD患者PMV风险的影响.
- 分析COPD中PMV相关的并发症风险.
主要方法:
- 使用高雄医科大学医院研究数据库 (2012-2020) 的数据进行了回顾性队列研究.
- 纳入标准:COPD诊断,年龄大于40岁. 排除标准:指数日期之前的PMV,不完整的记录.
- 倾向性得分匹配用于比较COPD和非COPD患者.
主要成果:
- 1.6% (60/3,744) 的COPD患者需要PMV.
- 与非COPD患者相比,COPD患者对PMV (2.21) 的调整HR显著更高.
- 糖尿病,高血压,心力衰竭,中风和慢性脏病等并发症大大增加了PMV风险.
结论:
- 年龄,性别和并发症是COPD患者PMV的重要风险因素.
- 伴随性疾病在PMV发生中发挥着关键作用,不仅仅是年龄.
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