含有西利托尔的口香糖和糖果可以预防儿童?
Darshini Ramasubbu1,2, Brett Duane3,4
1Dublin Dental University Hospital, Trinity College Dublin, Dublin, Republic of Ireland. RAMASUBD@TCD.IE.
Evidence-based dentistry
|May 25, 2024
概括
每日使用西利托的口香糖在中高风险的儿童中显示出显著的减少虫的效果. 在本系统性审查中,xylitol糖果没有显示出类似的预防益处.
科学领域:
- 儿科牙科 儿科牙科
- 皮肤病学 皮肤病学 皮肤病学
- 预防性牙科 预防性牙科
背景情况:
- 牙损仍然是儿童的重大公共卫生问题.
- 利醇是一种因其潜在的抗癌性质而被探索的糖替代品.
研究的目的:
- 评估西利托尔在降低儿童虫病发病率方面的有效性.
- 为了比较糖和糖果的预防作用.
主要方法:
- 随机对照试验和对照临床试验的系统审查和元分析.
- 在PubMed,Embase和Cochrane图书馆的数据库中搜索了1974-2022年间发表的研究.
- 包括的研究重点是儿童 (≤18岁) 患有虫作为结果,不包括含化物或其他混因素的研究.
主要成果:
- 十项关于糖醇口香糖的研究 (3466名参与者) 显示出具有统计学意义的减少虫的效果,其中9项研究表明了临床意义.
- 六项关于西利糖果的研究 (1023名参与者) 仅有一项研究具有显著的预防作用.
结论:
- 每天使用西利托尔口香糖似乎有效地减少中等至高虫风险的儿童虫的发生.
- 在分析的研究中,xylitol糖果没有显示出可比的虫预防效果.
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