非白人患者在经过跨动脉再血管化后,患中风的风险更高
Rohini J Patel1, Taiwo S Dodo-Williams1, Gabriela Sendek1
1Center for Learning and Excellence in Vascular & Endovascular Research (CLEVER), Division of Vascular and Endovascular Surgery, Department of Surgery, University of California San Diego, San Diego, California.
The Journal of surgical research
|May 26, 2024
概括
与白人患者相比,接受跨动脉再血管化 (TCAR) 的非白人患者面临更高的中风风险,但与白人患者相比,死亡率,心肌梗塞和静脉缩率相似.
科学领域:
- 血管外科 血管外科
- 健康差异 在健康上的差异
- 干预心脏病学 干预心脏病学
背景情况:
- 动脉复血管化传统上涉及动脉内切除术或支架.
- 之前的分析表明,非白人患者 (NWP) 的结果更差,包括中风和复原.
- 横动脉复血管化 (TCAR) 是一种较新的治疗选择,但其种族结果差异尚未研究.
研究的目的:
- 根据种族分层评估TCAR后的术后结果.
- 为了确定TCAR外科手术结果中的潜在种族差异.
主要方法:
- 分析了来自血管质量倡议 (2016-2021) 的22609名接受TCAR的患者.
- 患者被分为白色或非白色 (NWP).
- 使用后勤回归来比较结果,包括中风,心肌梗塞 (MI),死亡,静脉缩和返回手术室 (RTOR),并根据临床因素进行调整.
主要成果:
- 在对共变量进行调整后,NWP (9.7%) 与白人患者相比,在术后中风的风险增加了63% (OR=1.63,P=0.014).
- 在心脏病发作,死亡,TIA,缩或RTOR的几率方面没有观察到任何显著的种族差异.
- 该研究包括一个大队列,超过20,000名患者,提供了强大的统计能力.
结论:
- 经过TCAR的NWP有较高的中风风险.
- 在不同种族群体中,TCAR在死亡,心脏病发作,RTOR和缩方面表现出可比的安全性.
- 需要进一步的研究,以了解和减轻在动脉复血管化结果的种族差异的原因.
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