长时间工作和与代谢功能障碍相关的脂肪性肝病之间的关联:韩国的全国性基于人口的研究
1Department of Occupational and Environmental Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea; Graduate School, Yonsei University College of Medicine, Seoul, South Korea.
Public health
|May 26, 2024
概括
长时间的工作时间与韩国男性代谢功能障碍相关脂肪性肝病 (MASLD) 的风险增加有关. 这项研究强调了需要制定工作场所政策,以应对延长工作时间对健康的影响.
科学领域:
- 职业健康 职业健康 职业健康
- 代谢健康 代谢健康
- 肝病学 肝病学是一种肝病学.
背景情况:
- 长时间工作是各种代谢疾病的已知的危险因素.
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是全球日益严重的健康问题.
- 了解职业因素和MASLD之间的关系对于公共卫生至关重要.
研究的目的:
- 调查工作时间与MASLD的患病率之间的联系.
- 探索该协会中潜在的性别差异.
主要方法:
- 利用来自韩国国家健康和营养检查调查的22818名韩国工人的数据 (2013-2021年).
- 根据肝硬化和至少一个心脏代谢风险因素的存在来定义MASLD.
- 使用后勤回归计算赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 在男性中,MASLD的患病率为30.4%,在女性中为18.1%.
- 在男性中,每周工作≥55小时与超重/肥胖,糖尿病前期/糖尿病以及血压升高有关.
- 在男性工人中,在每周工作≥55小时和MASLD之间发现了显著的积极关联 (OR:1.27;95%CI:1.09-1.47).
- 在女性工人中没有观察到明确的关联.
结论:
- 在韩国男性工人中,长时间工作 (≥55小时/周) 与MASLD显著相关.
- 研究结果表明,需要采取政策干预措施,以减轻长时间工作对新陈代谢的不利影响.
- 可能需要进一步的研究来探索这种关联背后的机制和潜在的性别特异性影响.
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