在2024年联合国大会上确保可持续获得有效抗生素的进展:以目标为基础的方法
Marc Mendelson1, Joseph A Lewnard2, Mike Sharland3
1Division of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Lancet (London, England)
|May 26, 2024
概括
抗菌药物耐药性 (AMR) 威胁全球健康和发展. 新的目标是到2030年减少人类和动物的抗药性死亡率和不适当的抗生素使用,确保获得有效的治疗.
科学领域:
- 全球健康
- 传染性疾病
- 一个健康
背景情况:
- 抗菌药物耐药性 (AMR) 构成了严重的全球卫生危机,危及发展目标.
- 获得有效的抗生素是一个关键的挑战,
- 保持抗菌药物的有效性需要政治承诺,明确的目标,问责制和资金.
研究的目的:
- 提出2030年可行的全球目标来打击抗药性.
- 倡导一个平衡抗菌素耐药性减少和普遍获得抗生素的框架.
- 呼吁加强问责机制和全球科学合作.
主要方法:
- 建议在2030年之前实现"10-20-30"目标:将抗药性死亡率降低10%,人类使用抗生素降低20%,动物使用抗生素降低30%.
- 利用世界卫生组织的访问,观察,储备 (AWARE) 系统进行监测和评估.
- 包括改善感染预防,卫生和疫苗接种等策略,以支持AMR目标.
主要成果:
- 提出的"到2030年10-20-30"目标是雄心勃勃的,但可以实现的.
- 该系统为定义适当的抗生素使用和获取提供了框架.
- 综合公共卫生措施可以减轻低收入环境中抗生素使用的影响.
结论:
- 在联合国大会上迫切需要政治意愿和具体行动来解决AMR问题.
- 建立一个独立的抗菌素获取和耐药性小组对于问责制和指导至关重要.
- 实现全球抗菌药物耐药性目标需要采取协调的方法,重点是减少耐药性,确保获得基本药物的平等机会.
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